Abel Haggard is an elderly hunchback who haunts the remnants of his family's farm in the encroaching shadow of the Dallas suburbs, adrift in recollections of those he loved and lost long ago. Hundreds of miles to the south, in Austin, Seth Waller is a teenage "Master of Nothingness"--a prime specimen of that gangly breed of adolescent that vanishes in a puff of sarcasm at the slightest threat of human contact. When his mother is diagnosed with a rare disease, Seth sets out on a quest to find her lost relatives and uncover the truth of her genetic history. Though neither knows of the other's existence, Abel and Seth are linked by a dual legacy: the disease that destroys the memories of those they love, and the story of Isidora--a land without memory where nothing is ever possessed, so nothing can be lost. Blending myth, science, and dazzling storytelling, Stefan Merrill Block's extraordinary first novel illuminates the hard-learned truth that only through the loss of what we consider precious can we understand the value of what remains.